Dr.-Ing. Miko Schleinitz
antibodies and proteins is an emerging field in biotechnology due to their high specificity with antigens [1]. However, most of the proteins have a poor solubility in water and therefore their application is mostly [...] suitable additives shall be identified that increase the protein concentration up to 150 to 200 mg mL-1 to enable subcutaneous administration of these formulations with higher patient compliance. Description [...] applied to predict protein solubility on the basis of second osmotic virial coefficients. References [1] S. Mitragotri, P. A. Burke, and R. Langer: "Overcomming the Challenges in Administering Biopharmaceuticals: …
